A World Without Infectious Disease

Literature archive related to Vir science

Antibody Platform

Tackling influenza with broadly neutralizing antibodies
Davide Corti, Antonio Lanzavecchia
Current Opinion in Virology, 2017

Fcg receptor function and the design of vaccination strategies
Stylianos Bournazos and Jeffrey V. Ravetch
Immunity, 2017

Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody
Davide Corti, Antonio Lanzavecchia, Nancy J. Sullivan
Science, 2016

Cross-neutralization of four paramyxoviruses by a human monoclonal antibody
Davide Corti, Antonio Lanzavecchia
Nature, 2013

T Cell Platform

CD8+ T cell programming by cytomegalovirus vectors: applications in prophylactic and therapeutic vaccination
Klaus Frueh, Louis Picker
Current Opinion in Immunology, 2017

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E
Scott G. Hansen, Louis J. Picker
Science, 2016

Innate Immunity Platform

Sphingolipid biosynthesis induces a conformational change in the murine norovirus receptor and facilitates viral infection
Robert C. Orchard, Herbert W. Virgin
Nature Microbiology, 2018

Discovery of a proteinaceous cellular receptor for a norovirus
Robert C. Orchard, Herbert W. Virgin
Science, 2016

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon NOX2 and autophagy proteins
Jennifer Martinez, Herbert W. Virgin, Douglas R. Green
Nature Cell Biology, 2015

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection
Jacqueline M. Kimmey, Herbert W. Virgin, Christina L. Stallings
Nature, 2015

siRNA Platform

Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity
Maja M. Janas, Vasant Jadhav
Nature Communications, 2018